Can we use TCP over RF? Is there going to be an issue here about overloading the sender with NAK or NACK (negative-acknowledgement [ACK]) signals because we are getting many lost packets/packets out of order/etc.?

I found a white paper on this issue here: http://www.rtlogic.com/~/media/datasheets/whitepapers/rtl-mwp-079_adapting%20rfif%20over%20ip%20within%20range%20applications.pdf