When a BleuIO Dongle is connected to the Nucleo boards USB port the STM32 will recognize it. It will then accept 3 different inputs from the UART and send one of 3 preprogrammed commands to the BleuIO Dongle based on the input. The commands that are used in this example are:

ATI (Dongle Information)
AT+ADVSTART (Starts Advertising)
AT+ADVSTOP (Stops Advertising)
We have used a STM32 Nucleo-144 development board with STM32H743ZI MCU (STM32H743ZI micro mbed-Enabled Development Nucleo-144 series ARM® Cortex®-M7 MCU 32-Bit Embedded Evaluation Board) for this example.

If you want to use another setup you will have to make sure it support USB Host and beware that the GPIO setup might be different and may need to be reconfigured in the .ioc file.
Read more about it at
https://www.bleuio.com/blog/details.php?id=1356&title=Create-BLE-project