Your brake bleeding system project using Pi Picos and peristaltic pumps with LoRa for remote control sounds cool! If you're aiming for longer-range control, LoRa is a good fit; otherwise, Bluetooth works for short-range setups. Consider the distance and potential obstacles between your remote and the system for the best choice. Good luck with your project! 

The best pump for brake fluid is a pressure brake bleeder, which allows for efficient and effective bleeding of the brake system by applying pressure to the reservoir and forcing the fluid through the brake lines. This type of pump ensures a complete and air-free brake fluid exchange, promoting better brake performance and safety.

I bought a vacuum bleeder. Basically pulled the old fluid into a reservoir from the caliper, its the best thing ever. Makes the job super easy and very cheap. I understand the project for the sake of doing the project, but this is a solution if you need one for easy brake bleeding :)

every vehicle that I have bled the brakes on was done one wheel at a time, but those are all pre-ABS

Thanks for the input!

for what brake system do you want to build that?  A bicycle brake will be different to bleed to a old car or a modern car or even a truck...

Look at the commercial brake bleeding systems, some of them just apply a slight overpressure on the reservoir and use that to push the brake fluid.  Therefore no pump is needed, as shops have air pressure, it just needs a pressure regulator.

And on some modern cars nothing at all is needed as you can bleed with the ABS system, just hook a PC up. On such cars it can be that you must do it this way, otherwise not all channels inside the ABS system get flushed.

If you want to actually pump brakefluid make shure all materials are resistant against it, its a nasty thing.

It was for a '77 Jeep CJ-7 that's jacked up pretty high. I have to replace a valve in the brake system so the entire system has to be bled.

All of it is overkill ;) You could do this with a cable, dc motors and some switches. Bluetooth would probably be more overkill than lora (due to protocol simplicity), but lora is also overkill unless you need to bleed brake fluid from a kilometer away. Cheap wifi module or any 433 radio will probably suffice. Brake fluid should probably not be very conductive, so you can even have immersed motors with impellers to pump it, but for bleeding probably peristaltics are the best.

Yeah I was thinking the peristaltic mostly for cleanup afterward since the fluid would never actually be in contact with the pump.  The easiest for the wireless would probably be just to get Pico W's and put a small web server on each one.

This may all be a moot point though.  I realized last night that the vehicle I was thinking of building this for sits up so high that it's hard to get one tire off the ground with a normal jack, let alone all 4 at the same time.  That is unless I change Step 1 of the project to: "Buy a commercial vehicle lift"

Thanks for the input anyway!