For this project is specially designed Arduino nano drop in replacement:

Arduino nano drop-in replacement with samd21e18

This module enhance possibilities to powerful 32bit platform

and programming with: 

  • Adafruit Circuitpython etc. MU IDE
  • Microsoft Makecode 
  • Arduino IDE 

Thanks PCBway for support with board manufacturing! https://www.pcbway.com/

Can you imagine something more universal ?????
If yes, add comment, work in progress !!!