Without an actual device to test out the layout, it's somewhat difficult to get a full layout made. Additionally, since I haven't used many mathematic applications I still haven't started on TrueQuation. 

I've ordered the letters based on appearance (though 13K Hackaday log words iirc), with lower movement taking priority over lower average actuation force. I've also aligned the C, V and X locations for Copy/Paste/Cut commands.

For Finger5, there would be higher dedent resistance between row 2 and 3. Tetent Search is also forceless so that a user has a chance of stumbling on it by just sliding the Tetrinsic.

Row 5 of Finger5 is mainly for quick text navigation.